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What does neurofibromatosis affect?

  1. Muscles

  2. Peripheral nerves

  3. Blood vessels

  4. Cartilage

The correct answer is: Peripheral nerves

Neurofibromatosis primarily affects peripheral nerves, leading to the development of tumors called neurofibromas. These tumors can grow on nerves in various parts of the body and can cause a range of symptoms depending on their location. In addition to neurofibromas, neurofibromatosis can also cause other abnormalities in the nervous system, such as changes in skin pigmentation and other neurological issues. The characteristic tumors associated with neurofibromatosis result from genetic mutations that disrupt normal cell growth and differentiation in nerve tissue, making peripheral nerves the primary target of the condition.